When to Hold Clozaril: A Guide for Patients and Caregivers

Contact your doctor immediately if you experience any of the following:

    Fever or signs of infection: Clozaril significantly lowers your white blood cell count, increasing infection risk. Report any fever (over 100.4°F or 38°C), chills, sore throat, cough, or other infection symptoms. Seizures: Clozaril can lower the seizure threshold. Report any seizure activity immediately, including even minor episodes. Significant weight gain or changes in appetite: Monitor your weight regularly and report significant fluctuations. Unusual weight gain can be a side effect. Muscle stiffness or rigidity: These can be signs of a serious side effect called neuroleptic malignant syndrome (NMS). Seek medical attention at once. Severe drowsiness or dizziness: These may indicate a need for dosage adjustment. Changes in bowel movements: Constipation is a common side effect. Report significant changes in bowel habits. Tremors or involuntary movements: These could indicate tardive dyskinesia, a movement disorder. Report immediately. Excessive drooling: This can be a side effect, and should be reported. Yellowing of skin or eyes (jaundice): This suggests liver problems. Seek immediate medical help.

Regular blood tests are crucial while on Clozaril to monitor your white blood cell count. Follow your doctor’s instructions for these appointments diligently.

Always inform your doctor or pharmacist about all other medications you are taking, including over-the-counter drugs and supplements, as interactions can occur.

Keep a detailed record of your symptoms and medications. This information will be extremely helpful during your doctor’s visits.

Remember, adherence to prescribed dosage and regular check-ups are paramount for safe and effective Clozaril treatment. Don’t hesitate to contact your healthcare provider with any questions or concerns.