Sucralfate generally has a good safety profile, but some individuals experience side effects. Constipation is a common complaint. Drinking plenty of water and maintaining a high-fiber diet can help mitigate this. Darkening of stool is also possible; this is harmless and simply reflects the medication’s effect. Rarely, nausea or diarrhea occur.
While sucralfate is relatively safe, interactions with other medications are possible. It can reduce the absorption of some drugs, including tetracycline, quinidine, phenytoin, and ciprofloxacin. Therefore, maintain a four-hour interval between taking sucralfate and these medications. Always inform your doctor or pharmacist about all the medications you are taking, including over-the-counter drugs and supplements.
Aluminum accumulation is a potential long-term concern for patients on prolonged sucralfate therapy, particularly those with impaired kidney function. Regular monitoring of kidney function is advisable for these patients. Consult your doctor if you experience symptoms such as fatigue, weakness, bone pain, or changes in urination.
| Tetracycline | Reduced absorption | Separate administration by at least 4 hours |
| Quinidine | Reduced absorption | Separate administration by at least 4 hours |
| Phenytoin | Reduced absorption | Separate administration by at least 4 hours |
| Ciprofloxacin | Reduced absorption | Separate administration by at least 4 hours |
If you experience any concerning side effects, discontinue use and seek immediate medical attention. This information is for general knowledge and does not replace professional medical advice. Always consult your doctor before starting any new medication or if you have concerns about current medications.
