Handle finasteride with appropriate precautions. Its classification as a hazardous drug necessitates specific handling protocols to protect healthcare workers and the environment.
Personal Protective Equipment (PPE)
- Always wear powder-free gloves when handling finasteride, preferably nitrile or neoprene. Use a closed-system drug-transfer device (CSTDs) whenever possible to minimize exposure during preparation and administration. Consider wearing a gown, eye protection, and a respirator, especially during compounding or handling large quantities.
Safe Handling and Disposal
Prepare finasteride in a designated area with adequate ventilation. Use a biological safety cabinet (BSC) Class II, A2 or B2 for compounding. Minimize the generation of airborne particles. Avoid crushing or pulverizing tablets. Decontaminate all surfaces that come into contact with finasteride using an appropriate disinfectant. Follow manufacturer’s instructions carefully. Dispose of all contaminated waste materials according to your institution’s hazardous waste management plan. This usually involves special collection and disposal procedures.
Pregnancy Considerations
Finasteride is a teratogen. Women of childbearing age should avoid contact. Men handling finasteride should wash their hands thoroughly after handling the drug to prevent accidental exposure and transfer.
Monitoring and Training
- Regularly review and update your institution’s hazardous drug handling policies. Provide comprehensive training to all personnel involved in handling finasteride. Implement a monitoring program to track any incidents or exposures.
Specific Handling Protocols
Always consult your institution’s policies and relevant regulatory guidelines. These guidelines provide detailed, institution-specific procedures.
Further Resources
Seek additional information from the Occupational Safety and Health Administration (OSHA) and the United States Pharmacopeia (USP) on hazardous drug handling best practices.
