Doxycycline isn’t a first-line treatment for E. coli infections; consider it only after other antibiotics fail. Focus on confirming the E. coli strain’s susceptibility before prescribing. Laboratory testing is key for successful treatment.
Resistance patterns vary significantly geographically. Consult local antibiograms to guide your choice of antibiotics. Knowing regional resistance data optimizes treatment success and minimizes the spread of antibiotic-resistant bacteria.
If doxycycline is chosen, a typical adult dosage ranges from 100 to 200 mg daily, administered orally, divided into two doses. Always adhere to prescribed dosage and duration; premature discontinuation might lead to treatment failure and increased resistance. Monitor patients closely for adverse effects, including gastrointestinal upset and photosensitivity.
For severe E. coli infections, such as sepsis, intravenous administration might be necessary. Hospitalization provides better monitoring and enables prompt adjustment of treatment based on clinical response and laboratory results.
Remember, accurate diagnosis and targeted therapy are paramount. Prevention strategies, such as diligent handwashing and safe food handling practices, are crucial in minimizing E. coli infections.
