Avoid concurrent use of Zantac (ranitidine) and Cipro (ciprofloxacin) without consulting your doctor. Simultaneous intake may reduce Cipro’s effectiveness, potentially compromising its ability to fight infection. This is due to the impact ranitidine has on stomach pH, affecting Cipro’s absorption.
Ranitidine, a histamine H2 receptor antagonist, decreases stomach acid. Ciprofloxacin, a fluoroquinolone antibiotic, requires a slightly acidic environment for optimal absorption. Therefore, reducing stomach acidity with ranitidine can hinder Cipro’s absorption into the bloodstream, leading to lower drug levels and potentially treatment failure. This is especially crucial for serious infections requiring high Cipro concentrations.
If you’re prescribed both medications, discuss alternative treatment plans with your physician. They may recommend adjusting the dosage, timing of medication intake, or exploring alternative antibiotics that are less affected by changes in stomach pH. Open communication with your doctor ensures safe and effective treatment.
Remember: This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before making any changes to your medication regimen.