Both Cialis (tadalafil) and Viagra (sildenafil) treat erectile dysfunction by increasing blood flow to the penis. However, they achieve this through slightly different mechanisms and have varying durations of action.
Viagra inhibits an enzyme called phosphodiesterase-5 (PDE5). This allows increased levels of cyclic guanosine monophosphate (cGMP), a molecule crucial for smooth muscle relaxation in the penis. This relaxation facilitates blood vessel dilation, leading to an erection. Viagra’s effects generally last for 4-5 hours.
Cialis, similarly, inhibits PDE5. The key difference lies in its significantly longer half-life. This means Cialis remains active in the body for much longer, typically up to 36 hours, earning it the nickname “the weekend pill”. The prolonged action results from Cialis’s slower metabolism and clearance from the body.
While both drugs share the same general goal, individual responses can vary. Factors like age, overall health, and the presence of other medical conditions can influence their efficacy and potential side effects. Always discuss potential drug interactions with your doctor before combining these medications or taking them with other drugs.
Common side effects for both include headache, flushing, nasal congestion, and upset stomach. More serious side effects, though rare, include vision changes, hearing loss, and heart problems. Seek immediate medical attention if you experience any serious side effects.
