Sildenafil, while potentially beneficial for some pulmonary hypertension-related aspects of pulmonary fibrosis (PF), carries risks. Patients should be aware of these before starting treatment.
Common side effects include headaches, flushing, nasal congestion, and visual disturbances. These are usually mild and transient. However, more serious side effects, though less frequent, require immediate medical attention.
Hypotension is a significant concern, particularly in patients already experiencing low blood pressure. Careful monitoring of blood pressure is critical during treatment.
Cardiac events, such as arrhythmias and myocardial infarction, have been reported. Pre-existing heart conditions necessitate cautious consideration of sildenafil use, often necessitating thorough cardiac evaluation before starting treatment. This includes assessing the risk-benefit ratio carefully.
| Headache | Common | Mild to Moderate | Monitor, consider over-the-counter pain relief if needed. |
| Flushing | Common | Mild | Usually resolves spontaneously. |
| Nasal Congestion | Common | Mild | Usually resolves spontaneously. |
| Visual Disturbances | Common | Mild to Moderate | Monitor, report significant changes. |
| Hypotension | Uncommon | Severe | Seek immediate medical attention. |
| Cardiac Events | Rare | Severe | Seek immediate medical attention. |
Regular monitoring of vital signs, including blood pressure and heart rate, is essential during sildenafil therapy. Open communication with your physician about any new or worsening symptoms is crucial for safe management.
Individual responses to sildenafil vary. Your physician will tailor treatment based on your specific health status and the severity of your PF.
