Accutane, or isotretinoin, impacts rosacea primarily by reducing sebum production. This decrease in oil significantly lessens the inflammation that fuels many rosacea symptoms.
It also alters the composition of sebum, making it less likely to clog pores and trigger inflammatory reactions. This action helps to minimize the appearance of papules and pustules.
Furthermore, isotretinoin affects the growth and behavior of skin cells. It reduces the overproduction of keratin, which can contribute to pore blockage and inflammation in rosacea. This helps to prevent the formation of new lesions.
Finally, isotretinoin possesses anti-inflammatory properties that directly target the underlying inflammation in rosacea. This leads to a reduction in redness and overall skin irritation.