Sildenafil 50mg works by inhibiting a specific enzyme called phosphodiesterase-5 (PDE5).
This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscles of the penis. Higher cGMP levels relax these muscles, allowing increased blood flow.
- Increased blood flow is key to achieving and maintaining an erection. This process only works in response to sexual stimulation.
The result is improved erectile function.
Sexual stimulation triggers the release of nitric oxide. Nitric oxide activates an enzyme that increases cGMP. PDE5 normally breaks down cGMP, limiting blood flow. Sildenafil blocks PDE5, prolonging cGMP’s effects. This sustains blood flow to the penis, facilitating an erection.
Dosage and individual responses vary, so consulting a healthcare professional is crucial before using Sildenafil.
