Amoxicillin can interact with several medications, potentially altering their effectiveness or causing adverse reactions. Always inform your doctor or pharmacist of all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, before starting amoxicillin.
Methotrexate: Amoxicillin can increase methotrexate levels, potentially leading to increased side effects like bone marrow suppression. Close monitoring is necessary if you take both medications.
Oral contraceptives: Amoxicillin may reduce the effectiveness of oral contraceptives. Consider using additional birth control methods while taking amoxicillin and for a week after finishing the course.
Warfarin: Amoxicillin can alter the effects of warfarin, a blood thinner. Regular blood tests are crucial to monitor your INR (International Normalized Ratio) and ensure your blood clotting is within the therapeutic range.
Probenecid: Probenecid reduces the kidney’s excretion of amoxicillin, leading to higher amoxicillin blood levels. This can increase the risk of side effects. Your doctor may adjust the dosage of amoxicillin accordingly.
Allopurinol: Combining allopurinol with amoxicillin may increase the risk of skin rashes. Be vigilant for any skin changes and report them to your doctor immediately.
This information is not exhaustive. Consult your healthcare provider for a complete list of potential interactions and personalized advice.
