Avoid consuming alcohol while taking amoxicillin. Alcohol can interact with the antibiotic, potentially increasing the risk of side effects like nausea and vomiting.
Certain medications can interfere with amoxicillin’s effectiveness. Specifically, oral contraceptives may have reduced effectiveness. Discuss alternative birth control methods with your doctor.
Methotrexate, a drug used to treat certain cancers and autoimmune diseases, should not be taken concurrently with amoxicillin. The combination may increase the risk of methotrexate toxicity.
Warfarin, a blood thinner, may have its effects altered when taken with amoxicillin. Close monitoring of your INR (international normalized ratio) is necessary.
Allopurinol, used to treat gout, can potentially increase the risk of skin rashes when taken alongside amoxicillin.
Probenecid, sometimes used to treat gout, may increase amoxicillin levels in your blood, potentially leading to increased side effects. Your doctor should adjust the dosage accordingly.
| Oral Contraceptives | Reduced effectiveness | Discuss alternative birth control |
| Methotrexate | Increased toxicity risk | Avoid concurrent use |
| Warfarin | Altered blood thinning effect | Close INR monitoring |
| Allopurinol | Increased rash risk | Monitor for skin reactions |
| Probenecid | Increased amoxicillin levels | Dosage adjustment may be needed |
Always inform your doctor or pharmacist about all medications, supplements, and herbal remedies you are taking before starting amoxicillin. This includes over-the-counter drugs.
