Cefuroxime 500 mg twice daily (BID) is typically administered orally, with or without food. Dosage adjustments may be necessary based on the severity of the infection and patient-specific factors such as kidney function.
Oral Administration: Swallow the tablets whole with a full glass of water. Avoid crushing or chewing the tablets.
Duration of Treatment: The prescribed treatment duration varies depending on the infection. Always follow your doctor’s instructions regarding the treatment duration. Premature discontinuation may lead to treatment failure.
Missed Dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take a double dose to make up for a missed dose.
Renal Impairment: Dosage modification is required for patients with impaired kidney function. Your doctor will determine the appropriate dose based on your creatinine clearance.
| Normal Renal Function (Creatinine Clearance ≥ 60 mL/min) | Cefuroxime 500 mg BID |
| Mild Renal Impairment (Creatinine Clearance 30-59 mL/min) | Cefuroxime 500 mg once daily (QD) or a reduced dose BID |
| Moderate to Severe Renal Impairment (Creatinine Clearance | Dosage reduction or alternative antibiotic is usually required. Consult your physician. |
Adverse Reactions: Common side effects include diarrhea, nausea, and abdominal pain. Report any severe or persistent side effects to your doctor immediately. Allergic reactions, although rare, can be serious.
Drug Interactions: Inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements, as they may interact with cefuroxime.
Pregnancy and Breastfeeding: Use during pregnancy and breastfeeding should be carefully considered and only prescribed by a physician if the benefits outweigh the potential risks.
This information is for guidance only and does not substitute for professional medical advice. Always consult your doctor or pharmacist for personalized instructions.
