Anastrozole is a medication prescribed to reduce estrogen levels in the body. It achieves this by inhibiting aromatase, the enzyme responsible for converting androgens into estrogens.
How Anastrozole Works
Anastrozole specifically targets aromatase, thus preventing estrogen production. This makes it a selective aromatase inhibitor (AI).
- It’s primarily used to treat hormone-receptor-positive breast cancer in postmenopausal women. It’s also used in certain cases of male breast cancer. Off-label use includes fertility treatments and managing gynecomastia (enlarged breast tissue in men).
Important Considerations Before Using Anastrozole
Consult your doctor: Anastrozole isn’t suitable for everyone. Your doctor will assess your health status and determine if it’s appropriate for you. This includes discussing potential side effects and interactions with other medications. Bone health: Anastrozole can reduce bone density. Your doctor may recommend monitoring bone health through regular tests and possibly prescribing bone-strengthening medication. Cardiovascular risks: While studies are ongoing, some research suggests a possible link between AIs and increased cardiovascular risk. Open communication with your doctor about your cardiovascular health is crucial. Menopausal symptoms: Since it lowers estrogen levels, anastrozole can worsen menopausal symptoms like hot flashes, vaginal dryness, and mood changes. Your physician may recommend managing these symptoms through lifestyle changes or additional medication. Medication interactions: Anastrozole can interact with other medications. Inform your doctor about all medications, supplements, and herbal remedies you’re taking.
Side Effects
Common side effects include: hot flashes, joint pain, fatigue, nausea, headaches. Serious, though less common, side effects can occur and require immediate medical attention.
Dosage and Administration
Your doctor will determine the appropriate dosage based on your individual needs and health condition. Follow their instructions carefully; never alter the dosage without consulting them first.
